5E in most contexts refers to Dungeons & Dragons 5th Edition. DnD5E and D&D5E are other two common acronyms for the game.

On Roll20 there are available a number of character sheets that is suitable for 5E, and the following is a short description of each and their use.

Main Sheets

These are the four available 5E sheet, starting from the most popular and use sheets. D&D 5E by Roll20 is by far the most used, but there are still a good number of user for the other sheets, especially the Shaped sheet. The Scrolls-sheet is likely a good option for those who want use a simple sheet.

D&D 5E by Roll20

D&D 5E by Roll20 (AKA. "5th Edition OGL"), the Official 5E character sheet which includes the Charactermancer, and is by far the most used character sheet on Roll20. All game modules and adventures are designed to be compatible with this sheet. Receives updates almost daily.

In most cases when people don't mention which sheet (or game system) they use, one can mostly assume this is the one they are using.

D&D 5E (Shaped)

D&D 5E (Shaped), (AKA. just the "Shaped" sheet), is the second most popular 5E character sheet on Roll20. It have lot of automation, and customization options. Last updated In August 2019.

• Documentation
• Issue Tracker
• Sourcecode

DnD5E Community Contributed

DnD5E Community Contributed was created by John Myles and is one of the oldest character sheets on Roll20, and still have it's users. Last updated in March 2018.

• Sourcecode

D&D 5E (Scrolls)

A 5E sheet created by Chris Hall. Is designed to be flexible, memorable, and easy to use. Last updated in December 2016.

• Sourcecode & Readme

Other 5E-based sheets

There are a list of couple of other 5e-based sheet that aren't used for playing default 5E, but a variation of the system.

• D&D 5E Adventures in Middle Earth - For playing AiME
• D&D 5E (Darker Dungeons) - A flexible character sheet compatible with D&D 5e and Giffyglyph's Darker Dungeons-ruleset.
• Mass Effect - a supposed 5E conversion of a MAss Effect game, but the sheet doesn't seem to work.
• Star Wars 5e - a sheet made for playing the Star Wars 5E homebrew conversion of D&D5E
• Stargate - A simple 5E-based sheet to play the upcoming Stargate RPG.
• Unofficial Elder Scrolls Tabletop - Compatible for use with the UESTRPG conversion of DnD5E.